Characterization of the F8 gene: a silver lining in a dark cloud,Nature Reviews Cardiology

Haemophilia A is caused by variants in the gene that encodes coagulation factor VIII (FVIII). Sequencing of this gene in the 1980s was the initial step in developing replacement therapy with recombinant FVIII, and thereby removing the risk of blood-borne infections from plasma-derived FVIII.

中文翻译：

F8基因的表征：乌云中的一线希望

A 型血友病是由编码凝血因子 VIII (FVIII) 的基因变异引起的。 20 世纪 80 年代对该基因的测序是开发重组 FVIII 替代疗法的第一步，从而消除了血浆来源的 FVIII 引起血源性感染的风险。

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Characterization of the F8 gene: a silver lining in a dark cloud,Nature Reviews Cardiology

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